Q10 Stat
Modern lifestyles have increased the risk factors for cardiovascular and liver disease.
Cardiovascular diseases are the first cause of death worldwide. In Greece more than 360 people per 100.000 die every year from them. Statins are one of the most established treatments for the prevention and treatment of atherosclerotic cardiovascular diseases. However, their use has been associated with the occurrence of adverse effects such as myopathy and the risk of liver damage.
The efficient functioning of the liver is necessary for the proper functioning of the gastrointestinal tract as well as for general health. Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease and is associated with an increased risk of atherosclerotic cardiovascular disease, independent of the presence of diabetes mellitus, hypertension and obesity.
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Libytec pharmaceutical has developed Q10Stat an innovative combination containing CoQ10, selenium, choline, artichoke and milk thistle extract and vitamins C, B1, B6, and B12.
The primary function of CoQ10 is its involvement in intracellular energy production. Statins, in addition to reducing the synthesis of cholesterol, also reduce the synthesis of other substances such as CoQ10 and selenoproteins.
Regardless of this reduction, tissue concentrations of CoQ10 decrease with age and its dietary intake is usually not sufficient in pathological conditions.
In clinical practice, the addition of CoQ10 to statin therapy effectively reduces muscle symptoms, while its addition to conventional therapy in patients with chronic heart failure:
- improves symptoms
- significantly reduces major adverse cardiovascular events
Another component of Q10Stat is choline, an essential molecule for the synthesis of certain neurotransmitters, cell membranes and lipoproteins. The liver is the main organ responsible for its metabolism. Choline contributes to:
- in the normal metabolism of homocysteine
- in normal lipid metabolism
- in maintaining normal liver function
Choline deficiency can:
- cause muscle damage and abnormal fat deposition in the liver
- lead to the development of NAFLD
The synergistic effects of Q10stat are enhanced by the presence of selenium, artichoke and thistle extracts which have a hepatoprotective effect and a beneficial effect on non-alcoholic fatty liver disease, as well as vitamins C, B1, B6 & B12 which contribute to homocysteine metabolism.
There is an important interdependence between CoQ10 and selenium. Selenium deficiency can prevent cells from achieving optimal concentrations of CoQ10, and also, sufficient concentrations of CoQ10 must be available for cells to benefit from optimal selenium function.
Artichoke extracts affect lipid metabolism by reducing the endogenous production of cholesterol and triglycerides and enhancing their excretion or redistribution. They also enhance the production of bile by increasing the amount of bile acids and cholesterol excreted in the bile.
The active ingredients of milk thistle may also have beneficial effects in non-alcoholic fatty liver disease and are able to neutralize the hepatotoxicity of many substances (ethanol, paracetamol, mushroom poisoning) because they have an action:
- as antioxidants by regulating intracellular glutathione content
- as permeability regulators that prevent hepatotoxic agents from entering hepatocytes
- as stimulators of liver regeneration
- as inhibitors of the transformation of hepatocytes into myofibroblasts
Vitamin C is one of the most powerful antioxidant agents and a scavenger of free radicals in biological systems. Diseases such as cardiovascular disorders are related to insufficient concentrations. Therefore, an optimal intake of vitamin C may help protect against atherosclerosis and its clinical consequences.
Vitamin B1 contributes to the normal functioning of the heart. Vitamins B6 and B12 contribute to the normal metabolism of homocysteine and to the reduction of tiredness and fatigue.
In summary, Q10Stat is a unique product with a double protective effect that can have a positive effect on:
- arteriosclerosis
- ischemic heart disease
- chronic heart failure
- hypertrophic cardiomyopathy
- hypertension
- statin-induced cardiomyopathy
- non-alcoholic fatty liver disease
Administration of Q10Stat can:
- Improves the heart energy balance
- Reduces symptoms in patients with heart failure
- Reduces major adverse cardiovascular events
- Treats and prevents muscle symptoms caused by statins
- It has a hepatoprotective effect
- Helps regulate liver enzymes
- It can be co-administered with standard treatments
Administration of Q10Stat is recommended in:
- in those taking statins
- in those suffering from cardiovascular diseases
- for hepatoprotective action
